![\"\"\/](\"https:\/\/media.socastsrm.com\/wordpress\/wp-content\/blogs.dir\/1969\/files\/2019\/03\/1-21.jpg\")
<\/figure>\n\n\n\nErektil disfonksiyon ilac\u0131 PDE5 inhibit\u00f6rleri olarak bilinen bir ila\u00e7 s\u0131n\u0131f\u0131n\u0131n par\u00e7as\u0131d\u0131r. Uyar\u0131lma s\u0131ras\u0131nda penise kan ak\u0131\u015f\u0131n\u0131 iyile\u015ftirerek \u00e7al\u0131\u015f\u0131rlar, ereksiyon olmay\u0131 kolayla\u015ft\u0131r\u0131rlar. ED ila\u00e7 yan etkileri ve baz\u0131 ila\u00e7 etkile\u015fimleri potansiyeli ile birlikte gelir. ED i\u00e7in di\u011fer tedaviler aras\u0131nda ya\u015fam tarz\u0131 de\u011fi\u015fiklikleri, oral olmayan ila\u00e7lar ve do\u011fal ila\u00e7lar yer almaktad\u0131r.<\/p>\n\n\n\n
Ereksiyon olmak, hormonlar\u0131, baz\u0131 kimyasallar\u0131, v\u00fccuttaki sistemlerde birden fazla sistemi ve belki de bir veya iki erotik internet aramas\u0131n\u0131 i\u00e7eren karma\u015f\u0131k bir olaylar zinciridir. ED haplar\u0131 dik penis kan ak\u0131\u015f\u0131n\u0131 etkileyerek \u00e7al\u0131\u015f\u0131r, daha uzun s\u00fcre dik kalmas\u0131n\u0131 sa\u011flar. Ancak bu risksiz de\u011fildir – ED ila\u00e7lar\u0131, nas\u0131l \u00e7al\u0131\u015ft\u0131klar\u0131, riskler, faydalar ve ED i\u00e7in di\u011fer potansiyel tedaviler hakk\u0131nda her \u015feyi \u00f6\u011frenmek i\u00e7in okumaya devam edin.<\/p>\n\n\n\n
Erektil disfonksiyon nedir?<\/h1>\n\n\n\n![\"\"\/](\"http:\/\/www.drsinghals.com\/wp-content\/uploads\/2012\/10\/erectile-dysfunction-2.jpg\")
<\/figure>\n\n\n\nErektil disfonksiyon veya ED, tatmin edici bir cinsel ya\u015fam i\u00e7in ereksiyonu yeterince alamaman\u0131z veya yeterli tutamaman\u0131zd\u0131r. Bu, istedi\u011finiz kadar uzun s\u00fcrmeyen veya istedi\u011finiz kadar sa\u011flam olmayan ereksiyonlar\u0131 i\u00e7erebilir.<\/p>\n\n\n\n
ED’li insanlar genellikle durumun etraf\u0131ndaki utan\u00e7 veya damgalama ile u\u011fra\u015f\u0131rlar, ancak bu en yayg\u0131n cinsel sorunlardan biridir. 40 ila 70 ya\u015flar\u0131 aras\u0131ndaki Amerikal\u0131 erkeklerin tahmini% 52’si ED ile ilgilenir, ancak kesin say\u0131lar\u0131 bilmek zordur (bir\u00e7ok insan ED hakk\u0131nda konu\u015fmak i\u00e7in isteksizdir)(Sooriyamoorthy, 2021).<\/a><\/p>\n\n\n\nED’yi deneyimliyorsan\u0131z, bir sa\u011fl\u0131k uzman\u0131ndan t\u0131bbi yard\u0131m almak iyi bir fikirdir. Bunun nedeni, s\u00f6z konusu olabilecek sadece cinsel hayat\u0131n\u0131z de\u011fil, baz\u0131 erkeklerde ED’nin kalp hastal\u0131\u011f\u0131, y\u00fcksek tansiyon veya diyabet<\/strong>gibi ciddi bir altta bulunan durumun ilk i\u015fareti olmas\u0131d\u0131r.<\/p>\n\n\n\nED haplar\u0131 nelerdir?<\/h1>\n\n\n\n![\"\"\/](\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2020\/11\/HowToTakeViagra.png\")
<\/figure>\n\n\n\nED haplar\u0131 fosfodederaz tip 5 (PDE5) inhibit\u00f6rleri ad\u0131 verilen bir ila\u00e7 ailesinin bir par\u00e7as\u0131d\u0131r. \u015eu anda, ABD G\u0131da ve \u0130la\u00e7 \u0130daresi (FDA) taraf\u0131ndan onaylanan PDE5 inhibit\u00f6rleri <\/strong>\u015funlard\u0131r:( Dhaliwal, 2020<\/a>):<\/p>\n\n\n\n- Sildenafil (marka ad\u0131 Viagra)<\/li>
- Tadalafil (marka ad\u0131 Cialis)<\/li>
- Vardenafil (marka ad\u0131 Levitra veya Staxyn)<\/li>
- Avanafil (marka ad\u0131 Stendra)<\/li><\/ul>\n\n\n\n
\u0130lk PDE5 inhibit\u00f6r\u00fc sildenafil<\/strong>, ba\u015flang\u0131\u00e7ta y\u00fcksek tansiyonu tedavi etmek i\u00e7in re\u00e7eteli bir ila\u00e7 olarak form\u00fcle edilmi\u015ftir. Test edildik\u00e7e, ara\u015ft\u0131rmac\u0131lar beklenmedik bir yan etki ke\u015ffettiler: ilac\u0131 alan erkekler daha fazla ereksiyon bildiriyorlard\u0131 .<\/p>\n\n\n\nED haplar\u0131 nas\u0131l \u00e7al\u0131\u015f\u0131r?<\/h1>\n\n\n\n![\"\"\/](\"https:\/\/post.greatist.com\/wp-content\/uploads\/2020\/09\/Viagra_Table_1200x628-facebook-1200x628.jpg\")
<\/figure>\n\n\n\nEreksiyon, duyusal (dokunma, koku ve g\u00f6rme gibi) veya psikolojik (sizi tahrik eden bir \u015fey d\u00fc\u015f\u00fcnmek) olabilen stim\u00fclasyonla ba\u015flar.<\/p>\n\n\n\n
Cinsel uyar\u0131lma s\u0131ras\u0131nda, sinir mesajlar\u0131 penise “sertle\u015fme zaman\u0131!” der ve uyar\u0131lma ba\u015flar. Bu, penisin arterlerindeki d\u00fcz kaslar\u0131 gev\u015feten siklik guanosin monofosfat (cGMP) \u00fcretimini tetikler. Bu, hapsoldu\u011fu penise kan ak\u0131\u015f\u0131n\u0131 sa\u011flar, sert veya dik bir penis olu\u015fturur (Dhaliwal, 2020).<\/p>\n\n\n\n
Bo\u015falmadan sonra, PDE5 (daha \u00f6nce bahsetti\u011fimiz enzim) cGMP’yi par\u00e7alayarak ereksiyonu “kapat\u0131r”. CGMP par\u00e7aland\u0131ktan sonra, penis s\u0131k\u0131\u015fm\u0131\u015f herhangi bir kan\u0131 serbest b\u0131rak\u0131r ve ereksiyon azal\u0131r.<\/p>\n\n\n\n
ED ila\u00e7lar\u0131 PDE5’i (dolay\u0131s\u0131yla PDE5 inhibit\u00f6rleri ad\u0131) bloke ederek \u00e7al\u0131\u015f\u0131r ve cGMP’nin par\u00e7alanmas\u0131n\u0131 \u00f6nler. Sonu\u00e7, daha uzun s\u00fcre dik kalan engorged bir penistir. Sonu\u00e7, daha uzun s\u00fcre dik kalan engorged bir penistir (Dhaliwal, 2020).<\/p>\n\n\n\n
PDE5 inhibit\u00f6rleri ED tedavisinde olduk\u00e7a etkili olsa da, haplar\u0131n \u00e7al\u0131\u015fmas\u0131 i\u00e7in cinsel olarak uyar\u0131lmas\u0131 gerekti\u011fini bilmek \u00f6nemlidir.<\/p>\n\n\n\n
ED haplar\u0131 ne kadar etkilidir?<\/h1>\n\n\n\n
Ara\u015ft\u0131rmalar, d\u00fczg\u00fcn kullan\u0131ld\u0131\u011f\u0131nda, ED haplar\u0131n\u0131n erektil fonksiyonu iyile\u015ftirmeye yard\u0131mc\u0131 olabilece\u011fini g\u00f6stermi\u015ftir.<\/p>\n\n\n\n
Klinik verilerin b\u00fcy\u00fck bir analizi, sildenafil, tadalafil ve vardenafil alan kat\u0131l\u0131mc\u0131lar\u0131n (avanafil bu \u00e7al\u0131\u015fma zaman\u0131nda mevcut de\u011fildi) daha iyi ereksiyon ya\u015fad\u0131\u011f\u0131n\u0131 buldu. Asl\u0131nda, insanlar\u0131n yakla\u015f\u0131k% 70’i bu \u00fc\u00e7 haplardan birini kulland\u0131ktan sonra ereksiyonlar\u0131 veya daha ba\u015far\u0131l\u0131 cinsiyetleri geli\u015ftirdi. Analiz, \u00e7al\u0131\u015f\u0131lan ila\u00e7lar aras\u0131nda etkinlik veya yan etkilerde \u00f6nemli farkl\u0131l\u0131klar bulamad\u0131 (Tsertsvadze, 2009<\/a>).<\/p>\n\n\n\nED haplar\u0131 nas\u0131l kullan\u0131l\u0131r<\/h1>\n\n\n\n![\"\"\/](\"https:\/\/encrypted-tbn0.gstatic.com\/images?q=tbn:ANd9GcS7EWxF2OYHBrdkcIi3_fmbXd4DScwUwWnywH6i0kX_C_FEk-3OzvuPHTOLXA1rnKd4mzg&usqp=CAU\")
<\/figure>\n\n\n\nBelirtildi\u011fi gibi, ED haplar\u0131 ereksiyon daha g\u00fc\u00e7l\u00fc ve daha uzun \u00f6m\u00fcrl\u00fc olmas\u0131na yard\u0131mc\u0131 olabilir, ancak bir t\u00fcr stim\u00fclasyon olmadan size ereksiyon vermez.<\/p>\n\n\n\n
Genellikle hap\u0131 cinsel aktiviteden yakla\u015f\u0131k bir saat \u00f6nce a\u011f\u0131zdan al\u0131rs\u0131n\u0131z, ancak avanafil doza ba\u011fl\u0131 olarak seksnden 15 dakika \u00f6ncesine kadar al\u0131nabilir (Khera, 2020<\/a>).<\/p>\n\n\n\nEtkilerin ne kadar s\u00fcrece\u011fi, hangi ED ilac\u0131n\u0131 kulland\u0131\u011f\u0131n\u0131za ba\u011fl\u0131d\u0131r. Sildenafil yakla\u015f\u0131k 4-5 saat, avanafil 6 saat s\u00fcrer ve vardenafil 8 saate kadar \u00e7al\u0131\u015f\u0131r. Tadalafil, PDE5 inhibit\u00f6rlerinin en uzunu olan 36 saate kadar s\u00fcrer (Khera, 2020).<\/p>\n\n\n\n
ED ila\u00e7lar\u0131n\u0131n yan etkileri ve potansiyel riskleri<\/h1>\n\n\n\n
ED ila\u00e7lar yan etkiler ve ila\u00e7 etkile\u015fimleri potansiyeli ile birlikte gelir. PDE5 inhibit\u00f6rlerinin yayg\u0131n yan etkileri \u015funlard\u0131r (Dhaliwal, 2020):<\/p>\n\n\n\n
- Y\u0131kama (sildenafil ile daha deneyimli)<\/li>
- Mide veya haz\u0131ms\u0131zl\u0131k<\/li>
- Ba\u015f a\u011fr\u0131s\u0131<\/li>
- Ba\u015f d\u00f6nmesi<\/li>
- G\u00f6rme de\u011fi\u015fiklikleri (nesnelerin mavi bir tonlama olabilir)<\/li>
- Burun ak\u0131nt\u0131s\u0131 veya burun t\u0131kan\u0131kl\u0131\u011f\u0131<\/li>
- V\u00fccut a\u011fr\u0131lar\u0131 ve s\u0131rt a\u011fr\u0131s\u0131<\/li>
- D\u00fc\u015f\u00fck tansiyon<\/li><\/ul>\n\n\n\n
ED haplar\u0131n\u0131n nadir yan etkileri \u015funlard\u0131r (Dhaliwal, 2020):<\/p>\n\n\n\n
- Nonarteritik iskemik optik n\u00f6ropati olarak da adland\u0131r\u0131lan optik sinire inme<\/li>
- \u0130\u015fitme kayb\u0131<\/li>
- Priapizm (4 saat veya daha uzun s\u00fcren bir ereksiyon)<\/li><\/ul>\n\n\n\n
PDE5 inhibit\u00f6rleri ile cilt kanseri aras\u0131nda bir ba\u011flant\u0131 oldu\u011funu duymu\u015f olabilirsiniz. Bu ba\u011flant\u0131 i\u00e7in bir teori, ED ila\u00e7lar\u0131 alanlar\u0131n di\u011fer konular i\u00e7in bir sa\u011fl\u0131k hizmeti sa\u011flay\u0131c\u0131s\u0131 g\u00f6rme olas\u0131l\u0131\u011f\u0131n\u0131n daha y\u00fcksek olabilece\u011fidir, bu da cilt kanserine yakalanma \u015fans\u0131n\u0131 artt\u0131r\u0131r(Loeb, 2017<\/a>). \u015eimdiye kadar, ara\u015ft\u0131rmalar ED ila\u00e7lar\u0131n\u0131n ger\u00e7ekten cilt kanserine neden oldu\u011funu desteklemiyor(Feng, 2018<\/a>).<\/p>\n\n\n\nKalp hastal\u0131\u011f\u0131 olan ki\u015filerde g\u00f6\u011f\u00fcs a\u011fr\u0131s\u0131 ataklar\u0131n\u0131 tedavi etmek i\u00e7in kullan\u0131lan bir ila\u00e7 olan nitrat veya nitrogliserin kullan\u0131yorsan\u0131z oral ED ilac\u0131 almamal\u0131s\u0131n\u0131z. \u0130ki ilac\u0131n kar\u0131\u015ft\u0131r\u0131lmas\u0131 kan bas\u0131nc\u0131nda ciddi bir d\u00fc\u015f\u00fc\u015fe yol a\u00e7abilir(FDA, 2011<\/a>).<\/p>\n\n\n\nA\u015fa\u011f\u0131daki sa\u011fl\u0131k ko\u015fullar\u0131ndan herhangi birine sahipseniz ED haplar\u0131 kullanmaya dikkat edin (Dhaliwal, 2020):<\/p>\n\n\n\n
- Yak\u0131n bir kalp krizi veya fel\u00e7 \u00f6yk\u00fcs\u00fc (alt\u0131 ay veya daha az)<\/li>
- Kalp ritmi ile ilgili ciddi sorunlar<\/li>
- Y\u00fcksek veya d\u00fc\u015f\u00fck tansiyon<\/li>
- Kalp yetmezli\u011fi veya g\u00f6\u011f\u00fcs a\u011fr\u0131s\u0131 \u00f6yk\u00fcs\u00fc<\/li><\/ul>\n\n\n\n
Bir sa\u011fl\u0131k hizmeti sa\u011flay\u0131c\u0131s\u0131yla ED ila\u00e7lar\u0131 hakk\u0131nda konu\u015furken, sahip oldu\u011funuz t\u0131bbi durumlar\u0131n yan\u0131 s\u0131ra ald\u0131\u011f\u0131n\u0131z mevcut ila\u00e7lar\u0131 iyice tart\u0131\u015ft\u0131\u011f\u0131n\u0131zdan emin olun. \u00d6rne\u011fin alfa blokerler gibi baz\u0131 ila\u00e7lar yan etki riskini art\u0131rabilir.<\/p>\n\n\n\n
ED ila\u00e7lar\u0131n\u0131n maliyeti nedir?<\/h1>\n\n\n\n
\u00c7o\u011fu sigorta sa\u011flay\u0131c\u0131s\u0131 erektil disfonksiyon ila\u00e7lar\u0131n\u0131 kapsar, ancak sa\u011flay\u0131c\u0131n\u0131za dan\u0131\u015fmal\u0131s\u0131n\u0131z.<\/p>\n\n\n\n
Baz\u0131lar\u0131 sadece belirli bir ilac\u0131 kapsayabilir, t\u00fcm PDE5 inhibit\u00f6rlerini de\u011fil. Cepten \u00f6demeniz gerekiyorsa, maliyet marka ad\u0131 m\u0131 yoksa genel mi sat\u0131n ald\u0131\u011f\u0131n\u0131za ba\u011fl\u0131d\u0131r. Genel olarak, jenerik ila\u00e7lar marka ad\u0131 benzerlerinden daha ucuz olma e\u011filimindedir.<\/p>\n\n\n\n
Sildenafil ve tadalafil genellikle yeni vardenafilden daha ucuzdur. Avanafil ailenin en yenisi ve jenerik bir ila\u00e7 olarak mevcut de\u011fil. \u015eu anda d\u00f6rt ED tedavi se\u00e7ene\u011finin en pahal\u0131s\u0131.<\/p>\n\n\n\n
ED ba\u015fka nas\u0131l tedavi edilebilir?<\/h2>\n\n\n\nYa\u015fam tarz\u0131 de\u011fi\u015fiklikleri<\/h3>\n\n\n\n
Kardiyovask\u00fcler sisteminiz, penisiniz de dahil olmak \u00fczere kan\u0131 gitmesi gereken yere getirmek i\u00e7in gereklidir.<\/p>\n\n\n\n
Sa\u011fl\u0131kl\u0131 tutmak i\u00e7in sigaradan ka\u00e7\u0131n\u0131n, d\u00fczenli egzersiz yap\u0131n ve kalp sa\u011fl\u0131\u011f\u0131na sahip bir diyet uygulay\u0131n. Orta ila yo\u011fun egzersizin ereksiyonlar\u0131 iyile\u015ftirdi\u011fi g\u00f6sterilmi\u015ftir (Silva, 2017<\/a>). Bir \u00e7al\u0131\u015fmada, meyve ve sebze al\u0131m\u0131n\u0131 art\u0131ran, alkol t\u00fcketimini azaltan ve daha az sigara i\u00e7en gen\u00e7 erkeklerin daha iyi erektil i\u015flevi vard\u0131(Mikoniatis, 2018)<\/a>. Hem t\u00fct\u00fcn hem de alkol, sa\u011fl\u0131kl\u0131 bir ereksiyon \u00fcreten kan damarlar\u0131na ve sinirlere zarar verebilir.<\/p>\n\n\n\nOral olmayan ila\u00e7lar<\/h3>\n\n\n\n
Alternatif tedavi se\u00e7enekleri aras\u0131nda penise veya \u00fcretraya enjekte edilebilen alprostadil gibi oral olmayan ED ila\u00e7lar\u0131 bulunur. D\u00fc\u015f\u00fck testosteron ED nedeni ise, testosteron replasman tedavisi bir yama, jel veya enjeksiyon \u015feklinde kullan\u0131labilir (Khera, 2020).<\/p>\n\n\n\n
T\u0131bbi cihazlar<\/h3>\n\n\n\n
Penis pompalar\u0131 (vakum yard\u0131mc\u0131 cihazlar\u0131) ve horoz halkalar\u0131 ED i\u00e7in yararl\u0131 olabilir. Bir penis pompas\u0131 penise kan \u00e7eker ve ereksiyon \u00fcretir. Penisin etraf\u0131na (veya penis ve testislerin etraf\u0131na) bir horoz halkas\u0131 yerle\u015ftirilir ve kan\u0131n dik bir penisten akmas\u0131n\u0131 korur.<\/p>\n\n\n\n
Bir \u00e7ubuk, yar\u0131 sert implant veya seks \u00f6ncesi \u015fi\u015firilebilen penis implantlar\u0131 da bir se\u00e7enektir (Khera, 2020).<\/p>\n\n\n\n
Do\u011fal ila\u00e7lar<\/h1>\n\n\n\n![\"\"\/](\"https:\/\/images-prod.healthline.com\/hlcmsresource\/images\/AN_images\/ginseng-root-on-cutting-board-1296x728.jpg\")
ginseng<\/strong><\/figcaption><\/figure>\n\n\n\nBaz\u0131 insanlar ED’ye kar\u015f\u0131 etkili olmak i\u00e7in do\u011fal ila\u00e7lar bulmu\u015flard\u0131r.<\/p>\n\n\n\n
Baz\u0131 \u00e7al\u0131\u015fmalar, DHEA<\/strong>, ginseng <\/strong>, L-arginin ve yohimbe <\/strong>gibi re\u00e7etesiz takviyelerin<\/strong>yararl\u0131 olabilece\u011fini g\u00f6stermektedir. Ancak, bu iddialar FDA taraf\u0131ndan onaylanmam\u0131\u015ft\u0131r ve bu alanlarda daha fazla ara\u015ft\u0131rmaya ihtiya\u00e7 vard\u0131r.<\/p>\n\n\n\nKaynak:- getroman<\/p>\n","protected":false},"excerpt":{"rendered":"
FERAGATNAME Herhangi bir t\u0131bbi sorunuz veya endi\u015feniz varsa, l\u00fctfen sa\u011fl\u0131k uzman\u0131n\u0131zla konu\u015fun. Sa\u011fl\u0131k Rehberi ile ilgili makaleler, t\u0131p toplumlar\u0131ndan ve […]<\/p>\n","protected":false},"author":2,"featured_media":15549,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center 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<\/figure>\n\n\n\nErektil disfonksiyon veya ED, tatmin edici bir cinsel ya\u015fam i\u00e7in ereksiyonu yeterince alamaman\u0131z veya yeterli tutamaman\u0131zd\u0131r. Bu, istedi\u011finiz kadar uzun s\u00fcrmeyen veya istedi\u011finiz kadar sa\u011flam olmayan ereksiyonlar\u0131 i\u00e7erebilir.<\/p>\n\n\n\n
ED’li insanlar genellikle durumun etraf\u0131ndaki utan\u00e7 veya damgalama ile u\u011fra\u015f\u0131rlar, ancak bu en yayg\u0131n cinsel sorunlardan biridir. 40 ila 70 ya\u015flar\u0131 aras\u0131ndaki Amerikal\u0131 erkeklerin tahmini% 52’si ED ile ilgilenir, ancak kesin say\u0131lar\u0131 bilmek zordur (bir\u00e7ok insan ED hakk\u0131nda konu\u015fmak i\u00e7in isteksizdir)(Sooriyamoorthy, 2021).<\/a><\/p>\n\n\n\n ED’yi deneyimliyorsan\u0131z, bir sa\u011fl\u0131k uzman\u0131ndan t\u0131bbi yard\u0131m almak iyi bir fikirdir. Bunun nedeni, s\u00f6z konusu olabilecek sadece cinsel hayat\u0131n\u0131z de\u011fil, baz\u0131 erkeklerde ED’nin kalp hastal\u0131\u011f\u0131, y\u00fcksek tansiyon veya diyabet<\/strong>gibi ciddi bir altta bulunan durumun ilk i\u015fareti olmas\u0131d\u0131r.<\/p>\n\n\n\n ED haplar\u0131 fosfodederaz tip 5 (PDE5) inhibit\u00f6rleri ad\u0131 verilen bir ila\u00e7 ailesinin bir par\u00e7as\u0131d\u0131r. \u015eu anda, ABD G\u0131da ve \u0130la\u00e7 \u0130daresi (FDA) taraf\u0131ndan onaylanan PDE5 inhibit\u00f6rleri <\/strong>\u015funlard\u0131r:( Dhaliwal, 2020<\/a>):<\/p>\n\n\n\n \u0130lk PDE5 inhibit\u00f6r\u00fc sildenafil<\/strong>, ba\u015flang\u0131\u00e7ta y\u00fcksek tansiyonu tedavi etmek i\u00e7in re\u00e7eteli bir ila\u00e7 olarak form\u00fcle edilmi\u015ftir. Test edildik\u00e7e, ara\u015ft\u0131rmac\u0131lar beklenmedik bir yan etki ke\u015ffettiler: ilac\u0131 alan erkekler daha fazla ereksiyon bildiriyorlard\u0131 .<\/p>\n\n\n\n Ereksiyon, duyusal (dokunma, koku ve g\u00f6rme gibi) veya psikolojik (sizi tahrik eden bir \u015fey d\u00fc\u015f\u00fcnmek) olabilen stim\u00fclasyonla ba\u015flar.<\/p>\n\n\n\n Cinsel uyar\u0131lma s\u0131ras\u0131nda, sinir mesajlar\u0131 penise “sertle\u015fme zaman\u0131!” der ve uyar\u0131lma ba\u015flar. Bu, penisin arterlerindeki d\u00fcz kaslar\u0131 gev\u015feten siklik guanosin monofosfat (cGMP) \u00fcretimini tetikler. Bu, hapsoldu\u011fu penise kan ak\u0131\u015f\u0131n\u0131 sa\u011flar, sert veya dik bir penis olu\u015fturur (Dhaliwal, 2020).<\/p>\n\n\n\n Bo\u015falmadan sonra, PDE5 (daha \u00f6nce bahsetti\u011fimiz enzim) cGMP’yi par\u00e7alayarak ereksiyonu “kapat\u0131r”. CGMP par\u00e7aland\u0131ktan sonra, penis s\u0131k\u0131\u015fm\u0131\u015f herhangi bir kan\u0131 serbest b\u0131rak\u0131r ve ereksiyon azal\u0131r.<\/p>\n\n\n\n ED ila\u00e7lar\u0131 PDE5’i (dolay\u0131s\u0131yla PDE5 inhibit\u00f6rleri ad\u0131) bloke ederek \u00e7al\u0131\u015f\u0131r ve cGMP’nin par\u00e7alanmas\u0131n\u0131 \u00f6nler. Sonu\u00e7, daha uzun s\u00fcre dik kalan engorged bir penistir. Sonu\u00e7, daha uzun s\u00fcre dik kalan engorged bir penistir (Dhaliwal, 2020).<\/p>\n\n\n\n PDE5 inhibit\u00f6rleri ED tedavisinde olduk\u00e7a etkili olsa da, haplar\u0131n \u00e7al\u0131\u015fmas\u0131 i\u00e7in cinsel olarak uyar\u0131lmas\u0131 gerekti\u011fini bilmek \u00f6nemlidir.<\/p>\n\n\n\n Ara\u015ft\u0131rmalar, d\u00fczg\u00fcn kullan\u0131ld\u0131\u011f\u0131nda, ED haplar\u0131n\u0131n erektil fonksiyonu iyile\u015ftirmeye yard\u0131mc\u0131 olabilece\u011fini g\u00f6stermi\u015ftir.<\/p>\n\n\n\n Klinik verilerin b\u00fcy\u00fck bir analizi, sildenafil, tadalafil ve vardenafil alan kat\u0131l\u0131mc\u0131lar\u0131n (avanafil bu \u00e7al\u0131\u015fma zaman\u0131nda mevcut de\u011fildi) daha iyi ereksiyon ya\u015fad\u0131\u011f\u0131n\u0131 buldu. Asl\u0131nda, insanlar\u0131n yakla\u015f\u0131k% 70’i bu \u00fc\u00e7 haplardan birini kulland\u0131ktan sonra ereksiyonlar\u0131 veya daha ba\u015far\u0131l\u0131 cinsiyetleri geli\u015ftirdi. Analiz, \u00e7al\u0131\u015f\u0131lan ila\u00e7lar aras\u0131nda etkinlik veya yan etkilerde \u00f6nemli farkl\u0131l\u0131klar bulamad\u0131 (Tsertsvadze, 2009<\/a>).<\/p>\n\n\n\n Belirtildi\u011fi gibi, ED haplar\u0131 ereksiyon daha g\u00fc\u00e7l\u00fc ve daha uzun \u00f6m\u00fcrl\u00fc olmas\u0131na yard\u0131mc\u0131 olabilir, ancak bir t\u00fcr stim\u00fclasyon olmadan size ereksiyon vermez.<\/p>\n\n\n\n Genellikle hap\u0131 cinsel aktiviteden yakla\u015f\u0131k bir saat \u00f6nce a\u011f\u0131zdan al\u0131rs\u0131n\u0131z, ancak avanafil doza ba\u011fl\u0131 olarak seksnden 15 dakika \u00f6ncesine kadar al\u0131nabilir (Khera, 2020<\/a>).<\/p>\n\n\n\n Etkilerin ne kadar s\u00fcrece\u011fi, hangi ED ilac\u0131n\u0131 kulland\u0131\u011f\u0131n\u0131za ba\u011fl\u0131d\u0131r. Sildenafil yakla\u015f\u0131k 4-5 saat, avanafil 6 saat s\u00fcrer ve vardenafil 8 saate kadar \u00e7al\u0131\u015f\u0131r. Tadalafil, PDE5 inhibit\u00f6rlerinin en uzunu olan 36 saate kadar s\u00fcrer (Khera, 2020).<\/p>\n\n\n\n ED ila\u00e7lar yan etkiler ve ila\u00e7 etkile\u015fimleri potansiyeli ile birlikte gelir. PDE5 inhibit\u00f6rlerinin yayg\u0131n yan etkileri \u015funlard\u0131r (Dhaliwal, 2020):<\/p>\n\n\n\n ED haplar\u0131n\u0131n nadir yan etkileri \u015funlard\u0131r (Dhaliwal, 2020):<\/p>\n\n\n\n PDE5 inhibit\u00f6rleri ile cilt kanseri aras\u0131nda bir ba\u011flant\u0131 oldu\u011funu duymu\u015f olabilirsiniz. Bu ba\u011flant\u0131 i\u00e7in bir teori, ED ila\u00e7lar\u0131 alanlar\u0131n di\u011fer konular i\u00e7in bir sa\u011fl\u0131k hizmeti sa\u011flay\u0131c\u0131s\u0131 g\u00f6rme olas\u0131l\u0131\u011f\u0131n\u0131n daha y\u00fcksek olabilece\u011fidir, bu da cilt kanserine yakalanma \u015fans\u0131n\u0131 artt\u0131r\u0131r(Loeb, 2017<\/a>). \u015eimdiye kadar, ara\u015ft\u0131rmalar ED ila\u00e7lar\u0131n\u0131n ger\u00e7ekten cilt kanserine neden oldu\u011funu desteklemiyor(Feng, 2018<\/a>).<\/p>\n\n\n\n Kalp hastal\u0131\u011f\u0131 olan ki\u015filerde g\u00f6\u011f\u00fcs a\u011fr\u0131s\u0131 ataklar\u0131n\u0131 tedavi etmek i\u00e7in kullan\u0131lan bir ila\u00e7 olan nitrat veya nitrogliserin kullan\u0131yorsan\u0131z oral ED ilac\u0131 almamal\u0131s\u0131n\u0131z. \u0130ki ilac\u0131n kar\u0131\u015ft\u0131r\u0131lmas\u0131 kan bas\u0131nc\u0131nda ciddi bir d\u00fc\u015f\u00fc\u015fe yol a\u00e7abilir(FDA, 2011<\/a>).<\/p>\n\n\n\n A\u015fa\u011f\u0131daki sa\u011fl\u0131k ko\u015fullar\u0131ndan herhangi birine sahipseniz ED haplar\u0131 kullanmaya dikkat edin (Dhaliwal, 2020):<\/p>\n\n\n\n Bir sa\u011fl\u0131k hizmeti sa\u011flay\u0131c\u0131s\u0131yla ED ila\u00e7lar\u0131 hakk\u0131nda konu\u015furken, sahip oldu\u011funuz t\u0131bbi durumlar\u0131n yan\u0131 s\u0131ra ald\u0131\u011f\u0131n\u0131z mevcut ila\u00e7lar\u0131 iyice tart\u0131\u015ft\u0131\u011f\u0131n\u0131zdan emin olun. \u00d6rne\u011fin alfa blokerler gibi baz\u0131 ila\u00e7lar yan etki riskini art\u0131rabilir.<\/p>\n\n\n\n \u00c7o\u011fu sigorta sa\u011flay\u0131c\u0131s\u0131 erektil disfonksiyon ila\u00e7lar\u0131n\u0131 kapsar, ancak sa\u011flay\u0131c\u0131n\u0131za dan\u0131\u015fmal\u0131s\u0131n\u0131z.<\/p>\n\n\n\n Baz\u0131lar\u0131 sadece belirli bir ilac\u0131 kapsayabilir, t\u00fcm PDE5 inhibit\u00f6rlerini de\u011fil. Cepten \u00f6demeniz gerekiyorsa, maliyet marka ad\u0131 m\u0131 yoksa genel mi sat\u0131n ald\u0131\u011f\u0131n\u0131za ba\u011fl\u0131d\u0131r. Genel olarak, jenerik ila\u00e7lar marka ad\u0131 benzerlerinden daha ucuz olma e\u011filimindedir.<\/p>\n\n\n\n Sildenafil ve tadalafil genellikle yeni vardenafilden daha ucuzdur. Avanafil ailenin en yenisi ve jenerik bir ila\u00e7 olarak mevcut de\u011fil. \u015eu anda d\u00f6rt ED tedavi se\u00e7ene\u011finin en pahal\u0131s\u0131.<\/p>\n\n\n\n Kardiyovask\u00fcler sisteminiz, penisiniz de dahil olmak \u00fczere kan\u0131 gitmesi gereken yere getirmek i\u00e7in gereklidir.<\/p>\n\n\n\n Sa\u011fl\u0131kl\u0131 tutmak i\u00e7in sigaradan ka\u00e7\u0131n\u0131n, d\u00fczenli egzersiz yap\u0131n ve kalp sa\u011fl\u0131\u011f\u0131na sahip bir diyet uygulay\u0131n. Orta ila yo\u011fun egzersizin ereksiyonlar\u0131 iyile\u015ftirdi\u011fi g\u00f6sterilmi\u015ftir (Silva, 2017<\/a>). Bir \u00e7al\u0131\u015fmada, meyve ve sebze al\u0131m\u0131n\u0131 art\u0131ran, alkol t\u00fcketimini azaltan ve daha az sigara i\u00e7en gen\u00e7 erkeklerin daha iyi erektil i\u015flevi vard\u0131(Mikoniatis, 2018)<\/a>. Hem t\u00fct\u00fcn hem de alkol, sa\u011fl\u0131kl\u0131 bir ereksiyon \u00fcreten kan damarlar\u0131na ve sinirlere zarar verebilir.<\/p>\n\n\n\n Alternatif tedavi se\u00e7enekleri aras\u0131nda penise veya \u00fcretraya enjekte edilebilen alprostadil gibi oral olmayan ED ila\u00e7lar\u0131 bulunur. D\u00fc\u015f\u00fck testosteron ED nedeni ise, testosteron replasman tedavisi bir yama, jel veya enjeksiyon \u015feklinde kullan\u0131labilir (Khera, 2020).<\/p>\n\n\n\n Penis pompalar\u0131 (vakum yard\u0131mc\u0131 cihazlar\u0131) ve horoz halkalar\u0131 ED i\u00e7in yararl\u0131 olabilir. Bir penis pompas\u0131 penise kan \u00e7eker ve ereksiyon \u00fcretir. Penisin etraf\u0131na (veya penis ve testislerin etraf\u0131na) bir horoz halkas\u0131 yerle\u015ftirilir ve kan\u0131n dik bir penisten akmas\u0131n\u0131 korur.<\/p>\n\n\n\n Bir \u00e7ubuk, yar\u0131 sert implant veya seks \u00f6ncesi \u015fi\u015firilebilen penis implantlar\u0131 da bir se\u00e7enektir (Khera, 2020).<\/p>\n\n\n\n Baz\u0131 insanlar ED’ye kar\u015f\u0131 etkili olmak i\u00e7in do\u011fal ila\u00e7lar bulmu\u015flard\u0131r.<\/p>\n\n\n\n Baz\u0131 \u00e7al\u0131\u015fmalar, DHEA<\/strong>, ginseng <\/strong>, L-arginin ve yohimbe <\/strong>gibi re\u00e7etesiz takviyelerin<\/strong>yararl\u0131 olabilece\u011fini g\u00f6stermektedir. Ancak, bu iddialar FDA taraf\u0131ndan onaylanmam\u0131\u015ft\u0131r ve bu alanlarda daha fazla ara\u015ft\u0131rmaya ihtiya\u00e7 vard\u0131r.<\/p>\n\n\n\n Kaynak:- getroman<\/p>\n","protected":false},"excerpt":{"rendered":" FERAGATNAME Herhangi bir t\u0131bbi sorunuz veya endi\u015feniz varsa, l\u00fctfen sa\u011fl\u0131k uzman\u0131n\u0131zla konu\u015fun. Sa\u011fl\u0131k Rehberi ile ilgili makaleler, t\u0131p toplumlar\u0131ndan ve […]<\/p>\n","protected":false},"author":2,"featured_media":15549,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center 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haplar\u0131 nelerdir?<\/h1>\n\n\n\n
<\/figure>\n\n\n\nED haplar\u0131 nas\u0131l \u00e7al\u0131\u015f\u0131r?<\/h1>\n\n\n\n
<\/figure>\n\n\n\nED haplar\u0131 ne kadar etkilidir?<\/h1>\n\n\n\n
ED haplar\u0131 nas\u0131l kullan\u0131l\u0131r<\/h1>\n\n\n\n
<\/figure>\n\n\n\n
ED ila\u00e7lar\u0131n\u0131n yan etkileri ve potansiyel riskleri<\/h1>\n\n\n\n
ED ila\u00e7lar\u0131n\u0131n maliyeti nedir?<\/h1>\n\n\n\n
ED ba\u015fka nas\u0131l tedavi edilebilir?<\/h2>\n\n\n\n
Ya\u015fam tarz\u0131 de\u011fi\u015fiklikleri<\/h3>\n\n\n\n
Oral olmayan ila\u00e7lar<\/h3>\n\n\n\n
T\u0131bbi cihazlar<\/h3>\n\n\n\n
Do\u011fal ila\u00e7lar<\/h1>\n\n\n\n