{"id":6205,"date":"2022-09-14T15:59:01","date_gmt":"2022-09-14T15:59:01","guid":{"rendered":"https:\/\/fitolympia.com\/?p=6205"},"modified":"2022-09-14T15:59:02","modified_gmt":"2022-09-14T15:59:02","slug":"soybean-oil-linked-to-genetic-changes-in-brain-claims-study","status":"publish","type":"post","link":"https:\/\/fitolympia.com\/na\/soybean-oil-linked-to-genetic-changes-in-brain-claims-study\/","title":{"rendered":"Soybean oil linked to genetic changes in brain, claims study"},"content":{"rendered":"\n

Researchers discovered roughly 100 other genes also affected by the soybean oil diet<\/p>\n\n\n\n

\"\"\/<\/figure>\n\n\n\n

Consuming soybean oil may not only lead to obesity and diabetes, but also “affect neurological conditions like autism, and Alzheimer’s disease,” claims a study in mice by researchers, including one of Indian origin.<\/p>\n\n\n\n

Researchers from the University of California – Riverside (UCR) in the US noted that soybean oil is used for fast food frying, added to packaged foods, and fed to livestock in many parts of the world.<\/p>\n\n\n\n

The study, published in the journal Endocrinology, compared mice which were fed three different diets high in fat: soybean oil, soybean oil modified to be low in linoleic acid, and coconut oil.<\/p>\n\n\n\n

In 2015, the same research team found that soybean oil induces obesity, diabetes, insulin resistance, and fatty liver in mice.<\/p>\n\n\n\n

A 2017 study by the group showed that if soybean oil is engineered to be low in linoleic acid, it induces less obesity and insulin resistance.<\/p>\n\n\n\n

However, in the latest study, the researchers, including study first author Poonamjot Deol from UCR, did not find any difference between the modified and unmodified soybean oil’s effects on the brain.<\/p>\n\n\n\n

They found pronounced effects of the oil on the hypothalamus, a region of the brain where a number of critical processes take place.<\/p>\n\n\n\n

“The hypothalamus regulates body weight via your metabolism, maintains body temperature, is critical for reproduction and physical growth as well as your response to stress,” said Margarita Curras-Collazo, an associate professor at UCR, and lead author of the study.<\/p>\n\n\n\n

The team determined a number of genes in mice fed soybean oil were not functioning correctly.<\/p>\n\n\n\n

One such gene produces the “love” hormone, oxytocin. In soybean oil-fed mice, levels of oxytocin in the hypothalamus went down.<\/p>\n\n\n\n

The researchers discovered roughly 100 other genes also affected by the soybean oil diet.<\/p>\n\n\n\n

\"\"\/<\/figure>\n\n\n\n

They believe this discovery could have ramifications not just for energy metabolism, but also for proper brain function and diseases such as autism or Parkinson’s, the researchers said.<\/p>\n\n\n\n

However, it is important to note there is no proof that the oil causes these diseases, they said.<\/p>\n\n\n\n

The team noted the findings only apply to soybean oil — not to other soy products, or to other vegetable oils.<\/p>\n\n\n\n

\"\"\/<\/figure>\n\n\n\n

“Do not throw out your tofu, soymilk, edamame, or soy sauce,” said Frances Sladek, a UCR toxicologist, and professor of cell biology.<\/p>\n\n\n\n

“Many soy products only contain small amounts of the oil, and large amounts of healthful compounds such as essential fatty acids and proteins,” Sladek said.<\/p>\n\n\n\n

Since the research was conducted in mice, the researchers caution that the study might not translate to the same results in humans.<\/p>\n\n\n\n

As oxytocin is so important for maternal health and promotes mother-child bonding, the researchers said similar studies need to be performed using female mice.<\/p>\n\n\n\n

The researchers have not yet isolated which chemicals in the oil are responsible for the changes they found in the hypothalamus.<\/p>\n\n\n\n

However, they have ruled out two candidates: linoleic acid, since the modified oil also produced genetic disruptions, and stigmasterol — a cholesterol-like chemical found naturally in soybean oil.<\/p>\n","protected":false},"excerpt":{"rendered":"

Researchers discovered roughly 100 other genes also affected by the soybean oil diet Consuming soybean oil may not only lead 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